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The guide contains twenty-four design patterns that are useful in cloud-hosted applications. Each pattern is provided in a common format that describes the context and problem, the solution, issues and considerations for applying the pattern, and an example based on Microsoft Azure. Each pattern also includes links to other related patterns.

The design patterns are allocated to one or more of the following eight categories: availability, data management, design and implementation, messaging, management and monitoring, performance and scalibility, resiliency, and secuity.